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天然化合物

カタログ番号	製品名	別名	ターゲット
T67904	Antiviral agent		HBV
	Antiviral agent is thiazolidin-4-one with anti-hepatitis B activity		HBV
T64396	Antiviral agent 38		Antiviral
	2H-Pyrido[2',1':3,4]pyrazino[1,2-b]indazole-3-carboxylic acid, 6-(1, 1-Dimethylethyl)-6, 7-Dihydro-10 -(3-methoxypropoxy)-2-oxo-, (6R)- has antibacterial and antiviral activity and can be used to study Hepatitis B virus.		Antiviral
T40258	Antiviral agent 8
	Antiviral agent 8, surpassing lead compounds crocin-1 and crocin-2, has been identified as a potent and promising candidate with enhanced antiviral activities.
T40320	Antiviral agent 5
	Antiviral agent 5 is a crucial intermediate utilized in the development of antiviral agents that specifically target 3C and 3CL proteases, which includes the SARS-CoV-2 M pro enzyme.
T60440	Antiviral agent 17
	Antiviral agent 17 (Compound 4) is an anti-infection agent that retains its strong antiviral effect in a human replicon assay with an EC50 of 0.015 μM. Antiviral agent 17 shows good antiviral activity against murine noro...
T77632	Antiviral agent 34		Antiviral , DNA/RNA Synthesis
	Antiviral agent 34 is an orally available, potent antiviral compound that inhibits influenza A and B viruses.Antiviral agent 34 inhibits the proliferation of influenza viruses by modulating RNA polymerase.Antiviral agent...		Antiviral , DNA/RNA Synthesis
T60673	Antiviral agent 18
	Antiviral agent 18 (Compound 5) shows good antiviral activity against murine norovirus. Antiviral agent 18 is an anti-infection agent that has the potential in infectious and malignant diseases research [1].
T63125	Antiviral agent 19
	Antiviral agent 19 (Compound 3) is a selective inhibitor of Zika virus (EC50: 1.3 μM) with low cytotoxicity.
T64166	Antiviral agent 20
	Antiviral agent 20 (Compound 17b) is a selective inhibitor of Zika virus (EC50: 4.5 μM) and exhibits low cytotoxicity.
T79567	Antiviral agent 35		Influenza Virus
	Antiviral agent 35 (compound 4d) serves as a potent orally active inhibitor of the influenza virus, targeting early stages of viral replication. It suppresses influenza-induced ROS accumulation, autophagy, and apoptosis,...		Influenza Virus
T63921	Antiviral agent 7
	Antiviral agent 7 is a peptide-based coating that kills viruses.
T63666	Antiviral agent 6
	Antiviral agent 6 showed excellent anti-TSWV effects in vivo (EC50: 188 mg/L).
T72562	Antiviral agent 23
	Antiviral Agent 23, an effective inhibitor of enterovirus 71 (EV71) with an EC50 value of 94 nM, also exhibits potent suppression of METTL3/METTL14 activity. This compound is employed in the research of infections.
T61856	Antiviral agent 10
	Antiviral agent 10 effectively inhibits the respiratory syncytial virus (RSV) [1], serving as a potent anti-viral compound.
T72593	Antiviral agent 9
	Antiviral agent 9 exhibits potent efficacy against HIV-1 with an EC50 value of 0.006 nM, indicating extremely low concentrations are sufficient to inhibit the virus. Additionally, it demonstrates a selectivity index (SI)...
T79334	Antiviral agent 36		DNA/RNA Synthesis
	Antiviral agent 36 (compound 27), a potent inhibitor of both dengue (DENV) and Zika (ZIKV) viruses, demonstrates replication inhibition with EC50 values of 100 nM for ZIKV-FLR, 90 nM for ZIKV-HN16, 210 nM for DENV-2, and...		DNA/RNA Synthesis
T62780	Antiviral agent 15
	Antiviral agent 15 (Compound 15f) is a Clofazimine derivative with antiviral activity.Antiviral agent 15 inhibits rabies virus (EC50: 1.45 μM) and pseudotyped SARS-CoV-2 (EC50: 14.6 μM).
T62309	Antiviral agent 14
	Antiviral agent 14 is an antiviral agent that inhibits tobacco mosaic virus (TMV) (EC50: 135.5 μg/mL), and cucumber mosaic virus (CMV) (EC50: 178.6 μg/mL).
T75065	Antiviral agent 25
	Antiviral agent 25 (compound 6g), a novel non-peptide analog covalent inhibitor of SARS-CoV-2 3CL pro, exhibits robust inhibitory activity against both SARS-CoV-2 3CL pro and SARS-CoV-2 PL pro, with IC50 values of 0.118 ...
T82996	Antiviral agent 27
	Antiviral agent 27 (Compound 12) exhibits significant activity against the Ebola virus, with an EC50 value of 14 nM [1].
T79128	Antiviral agent 30
	Antiviral Agent 30 (Example 118) is an active compound against HCV and RSV with an inhibitory concentration (IC 50) of greater than 25μM [1].
T82995	Antiviral agent 33
	Antiviral agent 33 (compound 1c), a double-stranded DNA (dsDNA) virus inhibitor, exhibits potent inhibitory activity with IC50 values of 0.0790 µM for VACV and 0.1572 µM for AdV5, and is a candidate for oral administrati...
T9567	Samatasvir	ATOLIHZIXHZSBA-BTSKBWHGSA-N,IDX719	HCV Protease
	Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A.		HCV Protease
TNU0455	Antiviral agent 24
	Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors
T8877	Bonafton	Bonaphthone	Antiviral
	Bonafton (Bonaphthone) is an antiviral agent.		Antiviral
T60016	VV116	GS-621763-d1,JT001	SARS-CoV , RSV
	VV116 (JT001) is a selective and orally active nucleoside antiviral agent against respiratory syncytial virus (RSV) and SARS-CoV-2 infection.		SARS-CoV , RSV
T10445	B220		HSV
	B220, an antiviral agent, inhibits the growth of HSV-1, HSV-2, and human cytomegalovirus (CMV).		HSV
T16702	QL47		Virus Protease , BTK
	QL47 is a host-targeted small molecule antiviral agent with antiviral activity against dengue and other RNA viruses.QL47 acts as an inhibitor of viral translation and a covalent inhibitor of BTK, and can be used in the s...		Virus Protease , BTK
T0863	Idoxuridine	IDU,SKF 14287,5-Iodo-2′-deoxyuridine,NSC 39661,5-IUdR,Dendrid	Antifection , HSV
	Idoxuridine (Dendrid) is an analog of DEOXYURIDINE that inhibits viral DNA synthesis. The drug is used as an antiviral agent.		Antifection , HSV
T1598	Rimantadine hydrochloride	Rimantadine HCL,Flumadine,Meradane	Influenza Virus , DNA/RNA Synthesis
	Rimantadine hydrochloride (Meradane) is an RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.		Influenza Virus , DNA/RNA Synthesis
T8354	Triazavirin		Nucleoside Antimetabolite/Analog , Influenza Virus , DNA/RNA Synthesis
	Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.
T5832	Besifovir		HBV
	Besifovir, a parent drug converted by LB80380, further metabolizes to its active form, LB80317. LB80380 is potent antiviral agent against hepatitis B virus (HBV).		HBV
T0220	Foscarnet sodium	Phosphonoformate	Virus Protease , Reverse Transcriptase , DNA/RNA Synthesis
	Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.		Virus Protease , Reverse Transcriptase , DNA/RNA Synthesis
T12711	Retro-2 cycl	RN 1-001	Virus Protease
	Retro-2 cycl is a dihydroquinazolinone (DHQZ) retrograde trafficking inhibitor. Retro-2 cycl (RN 1-001) inhibits JCPyV and HPV16 pseudovirus(IC50s of 54 μM and 160 μM, respectively),with antiviral agent.		Virus Protease
T6676	Sofosbuvir	GS 7977,PSI-7977	HCV Protease
	Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment of chronic hepatitis C.		HCV Protease
T61652	WIN 54954		Antiviral
	WIN 54954 is an orally available antiviral agent that inhibits Coxsackievirus and inhibits viral translation or transcription.WIN 54954 may be useful in the study of small ribonucleic acid virus infections.		Antiviral
T1786	Daclatasvir dihydrochloride	BMS-790052 dihydrochloride	HCV Protease
	Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) is an orally available antiviral agent that inhibits the NS5A region of the hepatitis C virus (HCV) and is used in combination with other oral antiviral agents to ...		HCV Protease
T1220	Ethidium bromide	EtBr,Homidium bromide,EB	AChR
	Ethidium bromide (EB) A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucle...		AChR
T18928	Brilliant Black BN	E 151	Others , Virus Protease
	Brilliant Black BN (E 151) is an azo dye and a food colorant. It is a promising antiviral agent against EV71 infection via inhibiting the interaction between EV71 and its cellular uncoating factor cyclophilin A.		Others , Virus Protease
T0104	Umifenovir hydrochloride	Arbidol hydrochloride,Arbidol HCl	SARS-CoV , Influenza Virus
	Umifenovir hydrochloride (Arbidol HCl) , an broad-spectrum antiviral chemical agent, can inhibit cell invade of enveloped viruses by blocking viral fusion with host cell membrane.		SARS-CoV , Influenza Virus
T1428	Trifluridine	NSC 529182,Trifluorothymidine,5-Trifluorothymidine,NSC 75520,Viroptic,Trifluridina	Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , HSV
	Trifluridine (NSC-75520) is a fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibi...		Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , HSV
T9574	PF-07304814	Lufotrelvir
	Lufotrelvir (PF-07304814) is a phosphate prodrug of PF-00835231 which acts as a potent 3CL pro protease ( M pro ) inhibitor with SARS-CoV-2 antiviral activity. Lufotrelvir binds and inhibits SARS-CoV-2 3CL pro activity w...
T60272	Isatin-β-thiosemicarbazone	IBT	HSV
	Isatin-β-thiosemicarbazone is a potent inhibitor of herpes simplex virus (HSV). isatin-β-thiosemicarbazone exhibits antiviral activity by inhibiting both HSV-1 and HSV-2. isatin-β-thiosemicarbazone is Isatin-β-thiosemica...		HSV
T8972	FIT-039		Others , DNA/RNA Synthesis , CDK , HSV
	FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1). FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a pr...		Others , DNA/RNA Synthesis , CDK , HSV
T6501	Fludarabine Phosphate	NSC 312887 Phosphate,fludara Phosphate,F-ara-A (NSC 312887) Phosphate,F-ara-AMP	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	Fludarabine Phosphate (NSC 312887 Phosphate) is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Fludarabine phosphate is rapidl...
T24672	Z 124-73	Z-124-73
	Z 124-73 is an agent of antiviral.
T24455	Methisazone	Compound 33T57
	Methisazone is an effective antiviral agent against poxviruses.
T24713	Zimet 38-74	Zimet 38-74,Zimet 38-74;Z 38-74,Z 38-74
	Zimet 38-74 is an agent of antiviral.
T31628	Enisamium iodide	Amizon
	Enisamium iodide is used as an antiviral agent.
T25352	Droxinavir HCl	SC-55389A,SC 55389A,SC55389A,Droxinavir hydrochloride
	Droxinavir HCl is an antiviral agent and HIV protease inhibitor.

Compounds

Antiviral agent 38

T64396

Synonym:

Target: Antiviral

Antiviral agent 8

T40258

Synonym:

Target:

Antiviral agent 5

T40320

Synonym:

Target:

Antiviral agent 17

T60440

Synonym:

Target:

Antiviral agent 34

T77632

Synonym:

Target: Antiviral, DNA/RNA Synthesis

Antiviral agent 18

T60673

Synonym:

Target:

Antiviral agent 19

T63125

Synonym:

Target:

Antiviral agent 20

T64166

Synonym:

Target:

Antiviral agent 35

T79567

Synonym:

Target: Influenza Virus

Antiviral agent 7

T63921

Synonym:

Target:

Antiviral agent 6

T63666

Synonym:

Target:

Antiviral agent 23

T72562

Synonym:

Target:

Antiviral agent 10

T61856

Synonym:

Target:

Antiviral agent 9

T72593

Synonym:

Target:

Antiviral agent 36

T79334

Synonym:

Target: DNA/RNA Synthesis

Antiviral agent 15

T62780

Synonym:

Target:

Antiviral agent 14

T62309

Synonym:

Target:

Antiviral agent 25

T75065

Synonym:

Target:

Antiviral agent 27

T82996

Synonym:

Target:

Antiviral agent 30

T79128

Synonym:

Target:

Antiviral agent 33

Synonym: ATOLIHZIXHZSBA-BTSKBWHGSA-N,IDX719

Target: HCV Protease

Antiviral agent 24

Synonym: GS-621763-d1,JT001

Target: SARS-CoV, RSV

Target: Virus Protease, BTK

Idoxuridine

T0863

Synonym: IDU,SKF 14287,5-Iodo-2′-deoxyuridine,NSC 39661,5-IUdR,Dendrid

Target: Antifection, HSV

Rimantadine hydrochloride

T1598

Synonym: Rimantadine HCL,Flumadine,Meradane

Target: Influenza Virus, DNA/RNA Synthesis

Triazavirin

T8354

Synonym:

Target: Nucleoside Antimetabolite/Analog, Influenza Virus, DNA/RNA Synthesis

Synonym: Phosphonoformate

Target: Virus Protease, Reverse Transcriptase, DNA/RNA Synthesis

Retro-2 cycl

T12711

Synonym: RN 1-001

Target: Virus Protease

Sofosbuvir

T6676

Synonym: GS 7977,PSI-7977

Daclatasvir dihydrochloride

T1786

Synonym: BMS-790052 dihydrochloride

Target: HCV Protease

Ethidium bromide

T1220

Synonym: EtBr,Homidium bromide,EB

Target: Others, Virus Protease

Umifenovir hydrochloride

T0104

Synonym: Arbidol hydrochloride,Arbidol HCl

Target: SARS-CoV, Influenza Virus

Trifluridine

T1428

Synonym: NSC 529182,Trifluorothymidine,5-Trifluorothymidine,NSC 75520,Viroptic,Trifluridina

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, HSV

Isatin-β-thiosemicarbazone

Target: Others, DNA/RNA Synthesis, CDK, HSV

Fludarabine Phosphate

T6501

Synonym: NSC 312887 Phosphate,fludara Phosphate,F-ara-A (NSC 312887) Phosphate,F-ara-AMP

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Synonym: Compound 33T57

Target:

Zimet 38-74

T24713

Synonym: Zimet 38-74,Zimet 38-74;Z 38-74,Z 38-74

Synonym: SC-55389A,SC 55389A,SC55389A,Droxinavir hydrochloride

Target:

カタログ番号	製品名	別名	ターゲット
T3366	Cephalotaxine	ZINC19795976,(-)-Cephalotaxine,Cephalotaxlen	Antiviral , Influenza Virus
	Cephalotaxine (ZINC19795976) is an antiviral and an antitumor agent.		Antiviral , Influenza Virus
T4850	PCL 016	2-Picolinic acid	Virus Protease , Endogenous Metabolite
	PCL 016 (2-Picolinic acid) is a topical antiviral agent, which inhibits adenovirus replication in rabbit.		Virus Protease , Endogenous Metabolite
T9715	Aplidine		SARS-CoV , DNA/RNA Synthesis
	Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM).		SARS-CoV , DNA/RNA Synthesis
T7004	Tubercidin	Sparsomycin A,7-Deazaadenosine	Influenza Virus , DNA/RNA Synthesis , Antibacterial , Antibiotic
	Tubercidin (Sparsomycin A), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhib...
T5S2059	Glaucine		Calcium Channel , Dopamine Receptor , Influenza Virus , Adrenergic Receptor , PDE
	Glaucine has antitussive, antioxidative potential and antiviral activities, it may be an anti-arthritic agent, it can enhance LPS and zymosan-induced IL-10 production. Glaucine can inhibit the migration and invasion of h...
T5853	Rubitecan	RFS 2000,9-Nitrocamptothecin	Topoisomerase
	Rubitecan (9-Nitrocamptothecin) is a DNA topoisomerase I inhibitor. It inhibits DNA topoisomerase I and increases the fraction of supercoiled DNA in a cell-free assay in a concentration-dependent manner.Rubitecan is a se...		Topoisomerase
T4A2399	Cinobufotalin		IL Receptor , Akt , MRP , P-gp
	Cinobufotalin is a main cardiac toxin in toad, it is a novel anti-HCC agent, it induces growth inhibition and apoptosis in cultured HCC cells through ceramide production. Cinobufotalin is also an effective reversal agent...		IL Receptor , Akt , MRP , P-gp
T2S1865	Octyl gallate	Gallic acid octyl ester,n-Octylgallate,Octyl 3,4,5-trihydroxybenzoate,Progallin O,Stabilizer GA-8	Antioxidant , Influenza Virus , Reactive Oxygen Species , Antibacterial , Antifungal , HSV
	1. Octyl Gallate is an antioxidant approved by the US Food and Drug Administration (FDA) as a food additive. 2. Octyl Gallate has antimetastatic activity. 3. Octyl Gallate shows antimicrobial activity against H. pylori, ...
TN4932	Sageone		PARP , Akt , Caspase , Antifection
	Sageone represents a promising anticancer agent against gastric cancer that warrants further study, it synergizes with cisplatin cytotoxicity in SNU-1 human gastric cancer cells.Sageone also shows antiviral activity.		PARP , Akt , Caspase , Antifection
TMA1743	Ergosterol peroxide		ERK , VEGFR , p38 MAPK , Wnt/beta-catenin , Akt , JAK , CDK , JNK , STAT , Antifection
	Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Foxo3a activity by inhibiting pAKT and c-Myc and activating pr...
TN5288	Ergosterol peroxide glucoside	Ergosterol peroxide 3-O-β-D-glucopyranoside
	Ergosterol peroxide exhibits anti-cancer, amoebicidal, anticomplementary, antibacterial, antiviral, anti-oxdiant, and anti-melanogenic activities. Ergosterol peroxide could as an anti-atherosclerosis agent, it exhibits h...